UPDATED LATEST MCCQE EXAM COST - PERFECT MCCQE EXAM TOOL GUARANTEE PURCHASING SAFETY

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Updated Latest MCCQE Exam Cost - Perfect MCCQE Exam Tool Guarantee Purchasing Safety

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New Released Medical Council of Canada MCCQE Questions Verified by Experts [2025]

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Medical Council of Canada MCCQE Part 1 Exam Sample Questions (Q123-Q128):

NEW QUESTION # 123
On screening for dyslipidemia, a 45-year-old man is found to have a low high-density lipoprotein (HDL) cholesterol level. Which one of the following recommendations is the most appropriate?

  • A. Garlic supplementation.
  • B. Alcohol cessation.
  • C. Elimination of caffeine.
  • D. Low-salt diet.
  • E. Vigorous exercise program.

Answer: E

Explanation:
Low HDL is best managed with lifestyle changes such as increased aerobic physical activity, smoking cessation, and weight loss. Vigorous exercise has the strongest evidence for raising HDL levels.
Toronto Notes 2023 - Cardiology, Dyslipidemia:
"Increasing physical activity is among the most effective ways to raise HDL cholesterol. There is no consistent benefit to supplements such as garlic, nor does reducing salt or caffeine meaningfully raise HDL." MCCQE1 Objectives - Population Health > Cardiovascular Risk Management:
"Candidates should recommend evidence-based lifestyle interventions such as exercise to improve lipid profiles, particularly to increase HDL." Alcohol cessation (C) is generally beneficial for overall health but may actually lower HDL slightly. Garlic (D) and caffeine (E) are not evidence-based interventions for dyslipidemia.


NEW QUESTION # 124
A 72-year-old man reports that his wife says he has hearing trouble. Examination reveals that air conduction on the right side is less than on the left side and greater than bone conduction bilaterally. He hears a tuning fork placed on the top of his head better with his left ear. Which one of the following is the most appropriate next step in management?

  • A. Hearing aid.
  • B. Computed tomography scan of the head.
  • C. Wax removal from the ears by irrigation.
  • D. Audiometry.
  • E. Magnetic resonance imaging of the posterior fossa.

Answer: D

Explanation:
The patient demonstrates signs of asymmetric sensorineural hearing loss (SNHL). In Weber test, sound localizes to the better ear in SNHL. Air conduction > bone conduction on Rinne test bilaterally supports SNHL. Audiometry is the best next diagnostic step to quantify and characterize the hearing loss.
Toronto Notes 2023 - ENT, "Hearing Loss":
"Audiometry is the first-line investigation to distinguish conductive from sensorineural hearing loss and to assess severity and frequency involvement." MCCQE1 Objectives (Medicine > ENT > 20-1):
"Candidates must know the approach to hearing loss and interpret Weber and Rinne tests to guide investigations such as audiometry." Imaging (A, C) is reserved for red flags such as unilateral persistent SNHL, which may later prompt MRI to rule out acoustic neuroma. Wax removal (D) is for conductive loss. Hearing aids (E) are management, not diagnostic, and come after audiologic evaluation.


NEW QUESTION # 125
A 32-year-old primigravid woman is receiving magnesium sulfate for tocolysis. Her pregnancy is at 26 weeks' gestation. You suspect magnesium sulfate toxicity. Which one of the following is the first sign of magnesium sulfate toxicity?

  • A. Tachycardia
  • B. Hypotension
  • C. Oliguria
  • D. Tachypnea
  • E. Absent patellar reflexes

Answer: E

Explanation:
Magnesium sulfate toxicity is dose-dependent. The earliest and most sensitive clinical sign is theloss of deep tendon reflexes (especially patellar), which occurs before respiratory depression or cardiac changes.
Toronto Notes 2023 - Obstetrics Chapter:
"Toxicity from magnesium sulfate is progressive and typically presents first with loss of deep tendon reflexes.
Respiratory depression and cardiac arrest occur at higher serum levels. Regular monitoring of reflexes, respiratory rate, and urine output is essential." MCCQE1 Objectives (Obstetrics > 83-3: Preterm Labour and Tocolysis):
"The candidate must recognize early signs of magnesium sulfate toxicity including areflexia and respiratory depression." Tachycardia (B), hypotension (C), and tachypnea (D) are not typical early signs. Oliguria (E) may be a risk factor for accumulation but is not the first sign of toxicity.


NEW QUESTION # 126
A 3-year-old boy is brought to the office because he has progressive weight gain and short stature. He has marked truncal obesity, hypertrichosis of the upper lip, and facial swelling. Which one of the following is a physical examination most likely to reveal?

  • A. Cafe-au-lait spots
  • B. Hypertension
  • C. Thyroid goiter
  • D. Acanthosis
  • E. Hepatomegaly

Answer: B

Explanation:
Comprehensive and Detailed Explanation:
The child's presentation (weight gain, short stature, truncal obesity, facial swelling, hypertrichosis) is classic for Cushing syndrome. One of the hallmark findings on physical examination in pediatric Cushing syndrome is hypertension, due to increased cortisol-mediated mineralocorticoid receptor activation.
Toronto Notes 2023 - Pediatrics / Endocrinology:
"Cushing syndrome in children presents with growth failure, weight gain, moon facies, truncal obesity, and hypertension." MCCQE1 Objectives (Pediatrics > 77-2: Endocrine Disorders in Children):
"Candidates must identify clinical signs of hypercortisolism and evaluate for associated findings such as elevated blood pressure." Cafe-au-lait spots (A) suggest neurofibromatosis. Goiter (C) is more related to thyroid dysfunction.
Hepatomegaly (D) and acanthosis (E) are more commonly seen in metabolic syndrome or insulin resistance.
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NEW QUESTION # 127
A 56-year-old woman with a 4-year history of fibromyalgia presents for follow-up. She reports that she is struggling with her health and daily life. She is unhappy with her lack of progress and says she feels tired all the time and stays in bed all day. When asked why, she states she is confused about why she is not getting better. Physical exam and investigations are unchanged from baseline. Which one of the following is the best next step?

  • A. Educate the patient about her illness
  • B. Initiate iron and vitamin B12 supplementation
  • C. Start a selective serotonin reuptake inhibitor
  • D. Prescribe cannabinoid therapy

Answer: A

Explanation:
Patient education is foundational in managing fibromyalgia. Understanding the chronic but non-progressive nature of the disease, reassurance, and emphasis on self-management are crucial. It helps set realistic expectations and enhances engagement in therapy.
Toronto Notes 2023 - Rheumatology, Fibromyalgia:
"Patient education is essential. Explain the nature of fibromyalgia, emphasizing that although it is chronic, it is non-deforming and can be managed through exercise, sleep hygiene, and cognitive strategies." MCCQE1 Objectives - Psychiatry & Rheumatology > Chronic Pain Syndromes:
"Candidates must recognize the value of education and behavioral interventions in managing functional syndromes." SSRIs (D) may be used if depression is present. Iron/B12 (B) are not indicated without evidence of deficiency. Cannabinoids (A) lack strong evidence in fibromyalgia.


NEW QUESTION # 128
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